Curcumin For Ostearthritis

Curcumin for Osteoarthritis

Image of Tumeric root and powder

Curcumin is a Ayurvedic herb that comes from the herb tumeric and has been used in India for centuries. A study published in the journal Alternative Medicine Review included 100 patients with osterarthritis.

The new study compared the effects of NSAIDs with NSAIDs plus the Meriva supplement – composed of 20 percent natural curcuminoid mixture, 40 percent phosphatidylcholine, and 40 percent microcrystalline cellulose. Subjects in the active group received a daily dose of 1,000 mg, which provided a daily curcumin dose of 200 mg. The control group received “best available treatment NSAID’s”.

Researchers followed the participants for eight months and found changes in the Western Ontario and McMaster Universities (WOMAC) score, used to measure the osteoarthritis variables, decreased from 80.6 to 33.2 in patients receiving NSAIDs plus the curcumin supplement. Researchers also reported that WOMAC scores for pain decreased by 9.3 points, while no change was observed in the control group. Stiffness decreased from 7.4 to 3.2, with no significant changes in the control group.

According to Indena, the combining the soy phosphatidylcholine with curcumin works to boost the bioavailability of the spice. Blending curcumin with soy phosphatidylcholine allows it to, “interact via hydrogen bondings and polar interactions with the complementary group, like the polar heads of phospholipids”, says Indena.

These findings suggest that curcumin may be a beneficial long-term therapy approach for people suffering with osteoarthritis.

 

Source: Alternative Medicine Review
Volume 15, Number 4, Pages 337-344
“Efficacy and Safety of Meriva, a Curcumin-phosphatidylcholine Complex, during Extended Administration in Osteoarthritis Patients”
Authors: G. Belcaro; M.R. Cesarone; M. Dugall; L. Pellegrini; A. Ledda; M.G. Grossi; S. Togni; G. Appendino

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People with the Highest Levels of GLUTATHIONE are Living Past the Age of 100

Cutting-edge research is revealing the power of a “master antioxidant” – a tripeptide molecule called glutathione (GLUTATHIONE (GSH)).

People with the highest levels of GLUTATHIONE (GSH) are the ones who routinely live past 100. Plus, it may prevent a host of chronic diseases like arthritis, high blood pressure, heart disease, cancer and diabetes – just to name a few.
Best of all, boosting your levels of GLUTATHIONE (GSH) is easy. Below is an effective strategy that may add decades to your life. These include the best ways to get the most powerful forms of GLUTATHIONE (GSH) and how much to take.

When scientists at the University of Louisville gave mosquitoes a GLUTATHIONE (GSH) booster, their levels went up by 50 to 100 percent. And, their life spans increased by a remarkable 30 to 38 percent. Doctors at the Montreal General Hospital Research Institute in Canada then repeated the experiment with mice. They were able to duplicate the results – boosting levels of GLUTATHIONE (GSH) and increasing life spans.

Their success prompted others to investigate the effects of GLUTATHIONE (GSH) in humans. Odense University in Denmark compared levels of GLUTATHIONE (GSH) in centenarians (age 100 to 105) and people age 60 to 79 and found that GLUTATHIONE (GSH) was higher in the centenarians. Among the centenarian group, those who were the most active had the very highest levels.

In the same way that high levels of GLUTATHIONE (GSH) increase life spans, low levels of GLUTATHIONE (GSH) show a direct link to chronic degenerative diseases.

Here’s just a partial list:

• Heart Disease
• Cataracts
• Arthritis
• Renal Failure
• High Blood Pressure
• Leukemia
• Diabetes
• Hearing Loss
• Cancer
• Obstructive Lung Disease (COPD)
• Macular Degeneration

High levels of GLUTATHIONE (GSH) are associated with fewer illnesses. A University of Michigan study found that those with higher GLUTATHIONE (GSH) levels reported a greater sense of well being along with lower blood pressure, lower cholesterol and reduced body fat.

The most natural way to get more GLUTATHIONE (GSH) is eating foods high in glutathione. These include horseradish, broccoli, cauliflower, cabbage, kale and Brussels sprouts.

These nutritional supplements will also boost your GLUTATHIONE (GSH):

• Alpha Lipoic Acid (ALA)
• Melatonin
• Bilberry
• Grape Seed Extract
• Turmeric

There are also two reliable GLUTATHIONE (GSH) precursors – substances that stimulate the production of GLUTATHIONE (GSH). These are whey protein, commonly found in protein powders and N-acetyl cysteine (in a dose of 1,800 mg to 2,400 mg a day) – both are available at American Nutrition and/or local health food stores.

Finally, you can take GLUTATHIONE (GSH) supplements (1 to 2 grams per day). The latest reports show that up to 80 percent of most GLUTATHIONE (GSH) supplements are absorbed and used by your body.

contributed by Dr. Al Sears M.D.